- Indications for Use of Ibuprofen During Pregnancy
- Contraindications for the Prescription of Ibuprofen
- Ibuprofen Dosing and Administration
- Side Effects of Ibuprofen
Ibuprofen and Pregnancy
Ibuprofen during pregnancy is not prescribed. It belongs to the group of nonsteroidal anti-inflammatory drugs. It provides the following therapeutic effects on a woman's body – antipyretic, analgesic, anti-inflammatory. In addition, ibuprofen has an antiplatelet action i.e. it prevents blood clotting, which most often occurs in inflammatory reactions, compounding pathological changes.
The development of these effects is due to the blocking of cyclo-oxygenase which is involved in the synthesis of prostaglandins that cause the sensation of pain, inflammatory reaction, fever and so on. Ibuprofen is a selective inhibitor of cyclooxygenase, i. e. locks both the first and the second type of enzyme, in contrast, for example, from nimesil. This determines a greater incidence of side effects and contraindications for the prescription of ibuprofen.
The risk of ibuprofen during pregnancy is still in the fact that the duration of its use directly affects the increase in side effects that can not be useful to the fetus and the very pregnant woman. The drug is well absorbed, and after half an hour takes effect in the body, and the maximum action falls after 3 hours after application. But, again, during pregnancy ibuprofen is changed to safer medications.
Indications for Use of Ibuprofen During Pregnancy
Despite the fact that the prescription of ibuprofen during pregnancy is not recommended, we will touch on the main indications for its use. These are all conditions that are accompanied by pain of inflammatory origin, fever and the like.
Contraindications for the Prescription of Ibuprofen
In addition to pregnancy ibuprofen has other contraindications that are associated with the mechanism of the drug’s action.
The list of contraindications is as follows:
- individual hypersensitivity to the components of ibuprofen;
- ulcerative lesion of the mucous membrane of the gastrointestinal tract;
- bronchial asthma, which develops on aspirin (aspirin also relates to nonsteroidal anti-inflammatory drugs);
- caution should be exercised when using ibuprofen in case of apparent disorders of liver and kidney function.
Ibuprofen Dosing and Administration
Ibuprofen is not used during pregnancy. But out of pregnancy – you are welcome. Two to four pills in a single dose of the day are prescribed during which it is advised to take three times a day, up to 4 times. Ibuprofen pills should be taken with enough water to be taken regardless of the meal, as it has no effect on the activity of the drug action. Ointment of ibuprofen during pregnancy is also subject to all the contraindications, as are the pills. So be vigilant and careful.
Side Effects of Ibuprofen
Ibuprofen in the later stages of pregnancy, as well as the early ones can cause adverse reactions more likely than non-steroidal anti-inflammatory drugs of the last generation. Since prostaglandins are produced in all organs of the human body, so the side effects may occur from any system of the body.
These effects are:
- nausea, vomiting, abdominal pain, gastrointestinal bleeding;
- rapid breathing and a feeling of lack of air;
- sleep disturbances, mood swings, hallucinations;
- blurred vision;
- various allergic reactions (itching and rash, angioedema, toxic and allergic skin lesions, etc.)
There is a direct relationship – the longer the drug is taken, the greater the chance of side effects. Thus, the negative effects on the fetus determine the limits for the use of ibuprofen during pregnancy. In order to combat pain and fever one should use alternative medications that do not have harmful effects on the developing baby (from that group at a certain stage of pregnancy is possible to use indomethacin).